GNOM


Genomics & Biotechnology ETF

Reasons to Consider GNOM

High Growth Potential

Manufacturing genomic medicines is cumbersome, but new techniques using donated cells are more scalable and could slash production costs by 95%, potentially facilitating broader adoption.1

Structural Tailwinds

Recent regulatory approvals have helped genomic medicines gain momentum. Sales of genomic medicines are forecast to increase at a 39% compound annual growth rate from 2024-2030.2

Targeted Exposure

GNOM provides global exposure to emerging areas within the Health Care sector, at the intersection of science and technology.

1International Society for Cell and Gene Therapy, Feb 2019
2Evaluate Pharma, n.d., Technology Overviews of: Cell Therapy, Gene Therapy, Gene-Modified Cell Therapy, and Genome Editing, all accessed 1 Nov 2024

Key Information As of 02/21/25

Inception Date 04/05/19
Total Expense Ratio 0.50%
Net Assets $65.71 million
NAV $9.82

ETF Summary

The Global X Genomics & Biotechnology ETF (GNOM) seeks to invest in companies that potentially stand to benefit from further advances in the field of genomic science, such as companies involved in gene editing, genomic sequencing, genetic medicine/therapy, computational genomics, and biotechnology.

ETF Objective

The Global X Genomics & Biotechnology ETF (GNOM) seeks to provide investment results that correspond generally to the price and yield performance, before fees and expenses, of the Solactive Genomics Index.

Trading Details As of 02/21/25

Ticker GNOM
B3 Trading Code BGNO39
Bloomberg Index Ticker SOLGNOM
CUSIP 37954Y434
ISIN US37954Y4347
Primary Exchange Nasdaq
Shares Outstanding 6,690,000
Number of Holdings 42
30-Day Median Bid-Ask Spread 0.20%

Distributions As of 02/21/25

30-Day SEC Yield -0.38%
Distribution Frequency Semi-Annually

ETF Prices As of 02/21/25

NAV $9.82 Daily Change -$0.20 -2.00%
Market Price $9.83 Daily Change -$0.21 -2.09%

Performance History

Cumulative Returns (as of 01/31/25)
1 Month 6 Months YTD 12 Months 24 Months Since Inception Inception Date
Return GNOM 4.85% -12.47% 4.85% -5.48% -19.20% -33.33% 04/05/19
Returns (as of 02/20/25)
Return GNOM Return Index
Since Inception -34.31% -32.25%
12 Months -16.53% -15.91%
24 Months -20.39% -18.86%
Last 60 Trading Days 2.15% 2.24%
Last 75 Trading Days -5.29% -5.14%
Monthly Returns (through 02/20/25)
Return GNOM Return Index
Feb 2025 -1.47% -1.46%
Jan 2025 4.85% 4.87%
Dec 2024 -10.43% -10.37%
Nov 2024 4.53% 4.55%
Oct 2024 -7.83% -7.80%
Sep 2024 -1.42% -1.26%
Aug 2024 -1.88% -1.86%
Jul 2024 11.10% 11.20%
Jun 2024 2.86% 2.88%
May 2024 3.26% 3.28%
Apr 2024 -13.27% -13.23%
Mar 2024 -5.41% -5.20%
Feb 2024 11.62% 11.55%
Jan 2024 -7.01% -6.90%
Dec 2023 11.12% 11.12%
Nov 2023 17.53% 17.71%
Oct 2023 -12.70% -12.66%
Sep 2023 -9.53% -9.44%
Aug 2023 -8.41% -8.28%
Jul 2023 1.22% 1.27%
Jun 2023 -0.83% -0.71%
May 2023 -0.40% 0.01%
Apr 2023 -0.32% -0.36%
Mar 2023 -2.40% -2.28%
Feb 2023 -7.07% -7.73%

Total returns take into account management, administration and fees and other costs automatically deducted from the fund's assets. Before investing, you may read the prospectus in the “FEES AND EXPENSES” section for more details.

NAV & Index Chart

Top Holdings As of 02/21/25

Net Assets (%) Ticker Name Country SEDOL Market Price ($) Shares Held Market Value ($)
6.00 NTRA NATERA INC United States BYQRG48 162.31 24,284 3,941,536.04
5.29 VCYT VERACYTE INC United States BFTWZY0 39.18 88,753 3,477,342.54
4.74 BNTX BIONTECH SE-ADR United States BK6H543 120.01 25,946 3,113,779.46
4.56 CRSP CRISPR THERAPEUTICS AG United States BDHF4K6 47.91 62,599 2,999,118.09
4.52 BEAM BEAM THERAPEUTICS INC United States BK6L288 30.43 97,718 2,973,558.74
4.46 A AGILENT TECHNOLOGIES INC United States 2520153 135.37 21,660 2,932,114.20
4.38 ARWR ARROWHEAD PHARMA United States BYQBFJ8 19.90 144,587 2,877,281.30
4.27 BMRN BIOMARIN PHARMAC United States 2437071 68.25 41,142 2,807,941.50
4.10 TECH BIO-TECHNE CORP United States BSHZ3Q0 64.92 41,539 2,696,711.88
4.00 QGEN QIAGEN N.V. United States BS2CPH1 39.57 66,491 2,631,048.87
3.96 LEGN LEGEND BIOTECH CORP-ADR United States BMX9K07 39.70 65,525 2,601,342.50
3.72 ALNY ALNYLAM PHARMACE United States B00FWN1 250.59 9,755 2,444,505.45
3.70 1548 HK GENSCRIPT BIOTECH CORP Hong Kong BD9Q2J2 1.70 1,428,318 2,430,475.47
3.59 SRPT SAREPTA THERAPEUTICS INC United States B8DPDT7 106.28 22,179 2,357,184.12
3.41 RARE ULTRAGENYX PHARM United States BJ62Z18 42.59 52,650 2,242,363.50
3.00 RNA AVIDITY BIOSCIENCES INC United States BMWHPY1 31.12 63,425 1,973,786.00
2.92 MRNA MODERNA INC United States BGSXTS3 35.53 53,931 1,916,168.43
2.89 ILMN ILLUMINA INC United States 2613990 94.20 20,152 1,898,318.40
2.76 GILD GILEAD SCIENCES INC United States 2369174 109.95 16,495 1,813,625.25
2.57 MYGN MYRIAD GENETICS INC United States 2614153 14.18 119,133 1,689,305.94
2.52 NTLA INTELLIA THERAPEUTICS INC United States BYZM6C2 12.17 136,035 1,655,545.95
2.28 CDNA CAREDX INC United States BP3YM74 22.29 67,272 1,499,492.88
2.25 TXG 10X GENOMICS INC-CLASS A United States BKS3RS7 10.90 135,833 1,480,579.70
2.24 VRTX VERTEX PHARM United States 2931034 484.24 3,033 1,468,699.92
1.82 RCKT ROCKET PHARMACEU United States BDFKQ07 10.47 114,269 1,196,396.43
1.75 VIR VIR BIOTECHNOLOGY INC United States BK4PZ38 9.57 120,152 1,149,854.64
1.20 QURE UNIQURE NV United States BJFSR88 12.84 61,354 787,785.36
1.00 MRVI MARAVAI LIFESC-A United States BMCWKZ2 4.11 160,153 658,228.83
0.94 VERV VERVE THERAPEUTICS INC United States BNKGXX2 7.28 85,098 619,513.44
0.83 PACB PACIFIC BIOSCIEN United States B4N8MH9 1.54 353,345 544,151.30
0.74 SANA SANA BIOTECHNOLOGY INC United States BMFJJ97 3.01 161,957 487,490.57
0.67 FLGT FULGENT GENETICS INC United States BYQBFQ5 16.46 26,882 442,477.72
0.67 RGNX REGENXBIO INC United States BZ0G875 7.27 60,598 440,547.46
0.61 ALLO ALLOGENE THERAPEUTICS INC United States BFZNYB7 2.17 183,657 398,535.69
0.43 SGMO SANGAMO THERAPEUTICS INC United States 2573083 1.07 264,780 283,314.60
0.32 EDIT EDITAS MEDICINE INC United States BZ8FPH3 1.92 108,410 208,147.20
0.25 TSVT 2SEVENTY BIO INC United States BMTXV88 2.61 63,948 166,904.28
0.23 CASH United States 1.00 149,637 149,637.08
0.22 CRBU CARIBOU BIOSCIENCES INC United States BNYJR68 1.31 109,400 143,314.00
0.19 LYEL LYELL IMMUNOPHARMA INC United States BN6MB18 0.70 182,203 127,669.64
0.00 E SCILEX HOLDING RESTRICTED United States 9A80I96 0.00 226,071 745.58
-0.02 OTHER PAYABLE & RECEIVABLES United States 1.00 -12,943 -12,943.30
Holdings are subject to change. "Cash" denotes U.S. dollars.

Sector Breakdown As of 01/31/25

Sector Weight (%)
Health Care 100.0

Source: AltaVista Research, LLC

Country Breakdown As of 01/31/25

Country Weight (%)
United States 82.8
Netherlands 5.8
Germany 4.7
Switzerland 3.8
China 2.9

Source: AltaVista Research, LLC

ETF Characteristics As of 02/20/25

Return on Equity -15.50%
Weighted Avg. Market Cap 14,776 M
2024 2025
Price-to-earnings -13.32 -19.26
Price-to-book value 2.73 3.27

Source: AltaVista Research, LLC

ETF Risk Stats As of 01/31/25

Versus Beta
S&P 500 1.25
MSCI EAFE 1.14
MSCI Emg. Mkts 0.88
Standard Deviation 28.50%

Source: AltaVista Research, LLC

TERMS OF USE

Global X Brasil Gestora de Investimentos Ltda. (“Global X Brasil”) is an asset manager authorized by the Brazilian Securities and Exchange Commission (“CVM”), constituted in the form of CVM Resolution No. 21/2021. Investing involves risks. The material on this site is for informational purposes only and does not constitute investment advice, recommendation, offer or solicitation to buy or sell any securities, funds, or strategies to any person in any jurisdiction in which an offer, solicitation, purchase, or sale would be illegal under the securities laws of such jurisdiction. Opinions expressed here are subject to change without notice. Reliance upon the information contained in this material is at the sole discretion of the reader. No securities regulator has confirmed the accuracy of any information contained herein. Access to the information on this site or the use of the services or information provided herein is prohibited by any person or entity in any jurisdiction or country where such distribution or use is contrary to local law, rules, or regulation. Investment in index funds (ETFs) involves risks, including detachment from the benchmark index and related to the liquidity of shares in the secondary market. Investment funds managed by Global X Brasil use strategies that can result in significant equity losses for their quota holders. Global X Brasil, its partners and employees are exempt of responsibility for any damages resulting directly or indirectly from the use of the information contained on this website.

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