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    GNOM

    Genomics & Biotechnology ETF

    Invest in GNOM

    Reasons to Consider GNOM

    High Growth Potential

    Manufacturing genomic medicines is cumbersome, but new techniques using donated cells are more scalable and could slash production costs by 95%, potentially facilitating broader adoption.1

    Targeted Exposure

    GNOM provides global exposure to emerging areas within the Health Care sector, at the intersection of science and technology.

    Structural Tailwinds

    Recent regulatory approvals have helped genomic medicines gain momentum. Sales of genomic medicines are forecast to increase at a 37% compound annual growth rate from 2024-2030.2

    1International Society for Cell and Gene Therapy, Feb 2019
    2Evaluate Pharma, n.d., Technology Overviews of: Cell Therapy, Gene Therapy, Gene-Modified Cell Therapy, and Genome Editing, all accessed 6 Jun 2025.

    Key Information As of 11/25/25

    Inception Date 04/05/19
    Total Expense Ratio 0.50%
    Net Assets $53.84 million
    NAV $45.83

    ETF Summary

    The Global X Genomics & Biotechnology ETF (GNOM) seeks to invest in companies that potentially stand to benefit from further advances in the field of genomic science, such as companies involved in gene editing, genomic sequencing, genetic medicine/therapy, computational genomics, and biotechnology.

    ETF Objective

    The Global X Genomics & Biotechnology ETF (GNOM) seeks to provide investment results that correspond generally to the price and yield performance, before fees and expenses, of the Solactive Genomics Index.

    Trading Details As of 11/25/25

    Ticker GNOM
    B3 Trading Code BGNO39
    Bloomberg Index Ticker SOLGNOM
    CUSIP 37960A214
    ISIN US37960A2143
    Primary Exchange Nasdaq
    Shares Outstanding 1,174,672
    Number of Holdings 50
    30-Day Median Bid-Ask Spread 0.76%

    Distributions As of 11/25/25

    30-Day SEC Yield -0.13%
    Distribution Frequency Semi Annually
     Distribution History

    ETF Prices As of 11/25/25

    NAV $45.83 Daily Change $0.84 1.87%
    Market Price $45.80 Daily Change $0.87 1.94%

    Performance History

    Premium Discount Chart
    Cumulative Returns (as of 10/31/25)
    		1 Month 6 Months YTD 12 Months 24 Months Since Inception Inception Date
    Return GNOM 16.92% 38.73% 17.28% 9.81% 9.30% -25.42% 04/05/19
    Returns (as of 11/25/25)
    		Return GNOM Return Index
    Since Inception -24.82% -22.26%
    12 Months 5.90% 6.33%
    24 Months 10.19% 11.39%
    Last 60 Trading Days 24.02% 24.20%
    Last 75 Trading Days 31.24% 31.47%
    Monthly Returns (through 11/25/25)
    		Return GNOM Return Index
    Nov 2025 0.81% 0.86%
    Oct 2025 16.93% 16.97%
    Sep 2025 5.87% 5.98%
    Aug 2025 5.75% 5.77%
    Jul 2025 3.10% 3.11%
    Jun 2025 8.47% 8.55%
    May 2025 -5.25% -5.25%
    Apr 2025 2.14% 2.06%
    Mar 2025 -13.01% -12.97%
    Feb 2025 -9.25% -9.20%
    Jan 2025 4.84% 4.87%
    Dec 2024 -10.43% -10.37%
    Nov 2024 4.53% 4.55%
    Oct 2024 -7.83% -7.80%
    Sep 2024 -1.42% -1.26%
    Aug 2024 -1.88% -1.86%
    Jul 2024 11.10% 11.20%
    Jun 2024 2.86% 2.88%
    May 2024 3.26% 3.28%
    Apr 2024 -13.27% -13.23%
    Mar 2024 -5.41% -5.20%
    Feb 2024 11.62% 11.55%
    Jan 2024 -7.01% -6.90%
    Dec 2023 11.12% 11.12%
    Nov 2023 17.53% 17.71%

    Total returns take into account management, administration and fees and other costs automatically deducted from the fund's assets. Before investing, you may read the prospectus in the “FEES AND EXPENSES” section for more details.

    NAV & Index Chart

    Top Holdings As of 11/25/25

    Full Holdings (.csv)
    Net Assets (%) Ticker Name Country SEDOL Market Price ($) Shares Held Market Value ($)
    5.74 GH GUARDANT HEALTH INC United States BFXC911 108.81 28,409 3,091,183.29
    5.20 ILMN ILLUMINA INC United States 2613990 129.64 21,605 2,800,872.20
    4.68 NTRA NATERA INC United States BYQRG48 236.49 10,648 2,518,145.52
    4.43 ARWR ARROWHEAD PHARMA United States BYQBFJ8 46.79 50,958 2,384,324.82
    4.14 BMRN BIOMARIN PHARMAC United States 2437071 56.29 39,589 2,228,464.81
    4.05 TECH BIO-TECHNE CORP United States BSHZ3Q0 65.85 33,104 2,179,898.40
    3.93 VRTX VERTEX PHARM United States 2931034 429.82 4,921 2,115,144.22
    3.92 QGEN QIAGEN N.V. United States BS2CPH1 48.56 43,507 2,112,699.92
    3.92 RNA AVIDITY BIOSCIENCES INC United States BMWHPY1 71.55 29,477 2,109,079.35
    3.82 MRNA MODERNA INC United States BGSXTS3 24.75 83,121 2,057,244.75
    3.79 WGS GENEDX HOLDINGS CORP United States BR841G5 167.52 12,192 2,042,342.88
    3.68 BNTX BIONTECH SE-ADR United States BK6H543 99.71 19,865 1,980,739.15
    3.59 PRAX PRAXIS PRECISION United States BQ721R4 184.25 10,488 1,932,414.00
    3.40 ALNY ALNYLAM PHARMACE United States B00FWN1 429.80 4,263 1,832,237.40
    3.39 VCYT VERACYTE INC United States BFTWZY0 49.38 37,008 1,827,455.04
    3.35 LEGN LEGEND BIOTECH CORP-ADR United States BMX9K07 28.19 63,899 1,801,312.81
    3.26 CRSP CRISPR THERAPEUTICS AG United States BDHF4K6 53.57 32,818 1,758,060.26
    2.69 RARE ULTRAGENYX PHARM United States BJ62Z18 33.53 43,139 1,446,234.98
    2.60 LLY ELI LILLY & CO United States 2516152 1,109.94 1,262 1,400,744.28
    2.20 BMY BRISTOL-MYERS SQUIBB CO United States 2126335 49.05 24,097 1,181,957.85
    2.13 AZN LN ASTRAZENECA PLC United Kingdom 0989529 185.79 6,172 1,146,682.83
    2.04 GILD GILEAD SCIENCES INC United States 2369174 127.12 8,663 1,101,240.56
    2.01 BEAM BEAM THERAPEUTICS INC United States BK6L288 24.69 43,839 1,082,384.91
    1.94 1548 HK GENSCRIPT BIOTECH CORP Hong Kong BD9Q2J2 1.94 539,318 1,043,631.02
    1.88 TXG 10X GENOMICS INC-CLASS A United States BKS3RS7 19.07 53,010 1,010,900.70
    1.60 TWST TWIST BIOSCIENCE CORP United States BGKG6G7 31.11 27,666 860,689.26
    1.59 SRPT SAREPTA THERAPEUTICS INC United States B8DPDT7 19.35 44,329 857,766.15
    1.36 QURE UNIQURE NV United States BJFSR88 27.96 26,226 733,278.96
    0.84 WVE WAVE LIFE SCIENCES LTD United States BYZG9R0 7.43 61,062 453,690.66
    0.80 CDNA CAREDX INC United States BP3YM74 17.90 24,133 431,980.70
    0.77 NTLA INTELLIA THERAPEUTICS INC United States BYZM6C2 8.55 48,755 416,855.25
    0.63 PACB PACIFIC BIOSCIEN United States B4N8MH9 2.63 129,269 339,977.47
    0.62 MYGN MYRIAD GENETICS INC United States 2614153 7.91 42,453 335,803.23
    0.55 RGNX REGENXBIO INC United States BZ0G875 13.45 22,157 298,011.65
    0.54 FLGT FULGENT GENETICS INC United States BYQBFQ5 30.85 9,479 292,427.15
    0.53 PSNL PERSONALIS INC United States BJQ0608 11.21 25,487 285,709.27
    0.52 A AGILENT TECHNOLOGIES INC United States 2520153 157.20 1,788 281,073.60
    0.52 VIR VIR BIOTECHNOLOGY INC United States BK4PZ38 6.44 43,421 279,631.24
    0.45 CVAC CUREVAC NV United States BN4RD42 5.28 45,849 242,082.72
    0.35 MRVI MARAVAI LIFESC-A United States BMCWKZ2 3.76 50,493 189,853.68
    0.34 LAB STANDARD BIOTOOLS INC United States B3D32T9 1.42 129,084 183,299.28
    0.30 PRME PRIME MEDICINE INC United States BPBJFM7 3.72 43,998 163,672.56
    0.30 MLAB MESA LABORATORIES INC United States 2553814 81.17 2,002 162,502.34
    0.27 STOK STOKE THERAPEUTICS INC United States BJQ05Z6 29.82 4,891 145,849.62
    0.23 RCKT ROCKET PHARMACEU United States BDFKQ07 3.10 40,638 125,977.80
    0.22 CRBU CARIBOU BIOSCIENCES INC United States BNYJR68 1.87 64,814 121,202.18
    0.22 EDIT EDITAS MEDICINE INC United States BZ8FPH3 2.39 50,530 120,766.70
    0.21 ARCT ARCTURUS THERAPE United States BKC9SX3 6.80 16,272 110,649.60
    0.20 SGMO SANGAMO THERAPEUTICS INC United States 2573083 0.42 264,844 109,936.74
    0.19 SANA SANA BIOTECHNOLOGY INC United States BMFJJ97 3.51 28,605 100,403.55
    0.04 CASH United States 1.00 24,461 24,461.03
    -0.02 OTHER PAYABLE & RECEIVABLES United States 1.00 -12,024 -12,024.04
    Holdings are subject to change. "Cash" denotes U.S. dollars.

    Sector Breakdown As of 10/31/25

    Sector Weight (%)
    Health Care 100.0

    Source: AltaVista Research, LLC

    Country Breakdown As of 10/31/25

    Country Weight (%)
    United States 81.7
    Netherlands 5.0
    Switzerland 4.9
    Germany 3.2
    China 2.4
    Britain 1.8
    Singapore 1.0

    Source: AltaVista Research, LLC

    ETF Characteristics As of 11/25/25

    Return on Equity -29.50%
    Weighted Avg. Market Cap 33,031 M
    2024 2025
    Price-to-earnings -16.18 -19.24
    Price-to-book value 4.90 6.75

    Source: AltaVista Research, LLC

    ETF Risk Stats As of 10/31/25

    Versus Beta
    S&P 500 2.67
    MSCI EAFE -1.61
    MSCI Emg. Mkts -0.67
    Standard Deviation 189.20%

    Source: AltaVista Research, LLC

    ETF Documents

    TERMS OF USE

    Global X Brasil Gestora de Investimentos Ltda. (“Global X Brasil”) is an asset manager authorized by the Brazilian Securities and Exchange Commission (“CVM”), constituted in the form of CVM Resolution No. 21/2021. Investing involves risks. The material on this site is for informational purposes only and does not constitute investment advice, recommendation, offer or solicitation to buy or sell any securities, funds, or strategies to any person in any jurisdiction in which an offer, solicitation, purchase, or sale would be illegal under the securities laws of such jurisdiction. Opinions expressed here are subject to change without notice. Reliance upon the information contained in this material is at the sole discretion of the reader. No securities regulator has confirmed the accuracy of any information contained herein. Access to the information on this site or the use of the services or information provided herein is prohibited by any person or entity in any jurisdiction or country where such distribution or use is contrary to local law, rules, or regulation. Investment in index funds (ETFs) involves risks, including detachment from the benchmark index and related to the liquidity of shares in the secondary market. Investment funds managed by Global X Brasil use strategies that can result in significant equity losses for their quota holders. Global X Brasil, its partners and employees are exempt of responsibility for any damages resulting directly or indirectly from the use of the information contained on this website.

    FOR EVALUATION OF THE PERFORMANCE OF AN INVESTMENT FUND, IT IS RECOMMENDED THE ANALYSIS OF AT LEAST 12 (TWELVE) MONTHS. INVESTMENT FUNDS DO NOT HAVE A GUARANTEE FROM THE ADMINISTRATOR, THE MANAGER, ANY INSURANCE MECHANISM OR CREDIT GUARANTEE FUND – FGC. INVESTMENTS IN FINANCIAL AND CAPITAL MARKETS ARE SUBJECT TO RISKS OF LOSS GREATER THAN THE TOTAL VALUE OF INVESTED CAPITAL. PAST PROFITABILITY DOES NOT REPRESENT A GUARANTEE OF FUTURE PROFITABILITY THE PROFITABILITY DISCLOSED IS NOT NET OF TAXES. READ THE PROSPECTUS, THE FORM OF COMPLEMENTARY INFORMATION, SHEET OF ESSENTIAL INFORMATION AND THE REGULATION BEFORE INVESTING. DESCRIPTION OF THE ANBIMA TYPE AVAILABLE IN THE FORM OF COMPLEMENTARY INFORMATION.

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